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Maleic acid
CAS No: 110-16-7
Formula: C4H4O4
Specification:
Appearance: White granules or crystalline powder
Assay: 99.0% - 101.0%
State of solution: Clarification
Appearance of solution: Qualified
Heavy metals (Pb): 10mg/kg max
Fe: 5mg/kg max
Fumaric acid 1.5% max
Sulphated ash: 0.1% max
Moisture: 2.0% max
Application:
Maleic acid is an industrial raw material for the production of glyoxylic acid by ozonolysis.
Maleic acid may be used to form acid addition salts with drugs to make them more stable, such as indacaterol maleate.
Maleic acid is used as a precursor to fumaric acid, dimethyl maleate and glyoxalic acid. It is an electrophile and acts as dienophine in Diels-Alder reactions. It reacts with drugs to form more stable addition salts like indacaterol maleate, carfenazine, chlorpheniramine, pyrilamine, methylergonovine and thiethylperazine. Its maleate ion is useful in biochemistry as an inhibitor of transaminase reactions.
